Food Allergies and Chronic Illness

 

Different types of food allergy.

The immediate or IgE mediated food allergy pattern is easily recognized because it involves quick and dramatic symptoms. It is also easily recognized be standard medical blood testing for allergies, or the skin scratch test. 

Delayed patterns of food allergy or IgG mediated food allergies are not so obvious and often go unrecognized. The ‘standard medical allergy skin tests do not show this problem nor do IgE antibody tests.  Also, because the reactions are very subtle and delayed for hours, or a day or more, they are very difficult to recognize.

The common specific problems that are obviously related to food allergy include asthma, rhinitis, otitis media, atopic dermatitis, urticaria, anaphylaxis, angioedema, celiac disease, dermatitis Herpetiformis, allergic gastroenteropathy, allergic arthritis and diabetes-especially type 1.

Many of the major unsolved disease of our civilization are either degenerative and/or inflammatory and many are recognized to be immune-mediated or hypersensitivity diseases. The delayed patterns of food allergy can be the cause of chronic and disabling hypersensitivity disease. The stakes are high both for individual patients and for the society as a whole. None of the common hypersensitivity diseases have been solved and most appear to rage on, afflicting increasing numbers of patients with chronic and disabling diseases.

Asthma, allergy, rheumatic diseases, autoimmune diseases, multiple sclerosis, diabetes, thyroiditis, psoriasis and diabetes are examples of hypersensitivity diseases that involve humoral and cell-mediated immunity. We use celiac disease - wheat allergy- as a prototype that demonstrates the prolific ability of food allergy to produce a wide range of diseases.

We think food allergy is a disease mechanism triggered common proteins in the diet. The main offending foods are staples such as cows’ milk, eggs, wheat, soy, corn and meat. Food allergy is commonly recognized in infants and young children. In older children and adults, food allergy is seldom recognized, although up to 25% of adults report some adverse reactions from eating specific foods.

Commonly quoted “expert” opinions tend to minimize the incidence and importance of food allergy. While the dogma is misleading, it represents vested interests and is remarkably persistent. The type 1 model of allergy is attractive to physicians and researchers, because of its relative simplicity and the ease of testing for sensitization; but it selects only a special population of people with IgE-mediated allergy. 

While this is an important reaction pattern, some physicians have claimed it is the only valid form of allergic reactions to food. Their opinion is not acceptable. A distinction between immediate, obvious allergic reactions and delayed, less obvious, chronic immune injury is useful.

The problem is not that 25% of people recognize symptoms from food ingestion, but that many more people do not recognize that food is making them ill. We hope the reader will take the time to find out why we think food allergy is such an important mechanism of disease and how to resolve common food-related health problems by diet revision. 

Antibody Test Helps Patients Overcome Symptoms Of Delayed Allergy; Practitioner Achieves Successful Clinical Outcomes With Igg Test

Grasp a red-hot pot handle, and you feel a searing pain in your hand. Nick your finger on a sharp kitchen knife, and blood seeps out almost instantly. In injuries like these, the cause is simple to ascertain, because the effect immediately follows in its tracks.

But imagine if the pain or wound didn’t show up until days after the event that caused it? Without seeing a clear, visible sequence, you might be hard-pressed to figure why your symptoms suddenly surfaced from “nowhere.”

A similar challenge faces people who suffer from delayed allergic reactions to food. These patients may experience fatigue, headaches, digestive problems, mood shifts, skin rashes, and other symptoms hours, or even days, after consuming an offending substance.

By measuring levels of immunoglobulin G (IgG) in the blood of these patients, however, and implementing dietary changes to avoid foods triggering a high IgG response, more than 70% of these symptoms may be successfully reduced or eliminated, according to a recently published clinical study by Hamilton S. Dixon, M.D. The study was originally presented at the Annual Meeting of the American Academy of Otolaryngic Allergy.

Dr. Dixon began the study by first identifying 114 patients who showed chronic symptoms of delayed food allergy based on their personal histories. This group included patients with inhalant allergy symptoms who did not improve after two months of immunotherapy based on previous allergy tests. “Delayed food allergy is highly suspect in allergic patients with negative IgE RAST or skin test results,” Dr. Dixon pointed out.

All the patients were tested for IgG levels and advised to follow a diet that partially or completely eliminated foods triggering strong responses. Of the eighty patients who complied with the dietary changes for six to twenty-two months after the test, more than 70% reported a dramatic clinical improvement of at least 75% for their symptoms.

“Of special interest were 20 patients with disabling symptoms,” observed Dr. Dixon. These patients “achieved an 80% or greater improvement level, with 20% of those achieving 100% improvement and 50% obtaining 90% or more relief.” Further follow-up on the compliant patients has been “borne out with excellent outcomes,” Dr. Dixon added.

Dr. Dixon advises IgG food testing “when chronic food allergy symptoms are present and conservative treatment has failed.” The test, he notes, offers several clinical advantages over food challenge tests for delayed symptoms, which are cumbersome and impractical, and over scratch or prick tests for foods, which are often unreliable (approximately 20% accuracy rate).

Besides treating chronic symptoms in adults, IgG testing also has great clinical potential for treating children with secretory otitis, who often require repeated tube insertions, suggests Dr. Dixon. Changing a child’s diet based on IgG response is likely to be much more economical than many other treatments for secretory otitis, which currently incurs total healthcare costs of over $2 billion a year.

NOTE: The Comprehensive Antibody Assessment measures both IgE and IgG responses to 88 general or 92 vegetarian foods, to pinpoint immune reactions that could be triggering immediate and delayed reactions to specific foods. An IgE Inhalant panel that is customized to reflect five different regions in the country is included as well.

As Dr. Dixon emphasizes, effective diet manipulation following IgG test results is the key to achieving successful clinical outcomes. For this reason, every Antibody Assessment report comes with a patient-friendly True Relief™ Rotation Diet Schedule, designed to reflect each patient’s unique antibody responses.

Source: Dixon HS. Treatment of delayed food allergy based on specific immunoglobulin G RAST testing. Otolaryngol Head Neck Sur 2000; 123:48-54.